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Understanding these variables can help clinicians and patients anticipate and manage symptoms more effectively

So, if you take 1,000 mcg (micrograms) of B12, you can absorb 10 mcg of B12, even if your complex absorption pathway is not functioning properly

Other recognized but rare complications of overdose include heart block, pancreatitis, acute renal failure, alopecia, leucopenia, thrombocytopenia, anaemia, optic nerve atrophy and acute respiratory distress syndrome [18, 50]

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Although they diverge in tone (spanning from categorical suspension to a more nuanced, patient-centered approach) their composite message forms a coherent clinical trajectory that underpins the risk-adapted algorithm described in Section 7