Details of the National Institutes of Health-funded study were published this week in a Nature paper titled A brain reward circuit inhibited by next-generation weight-loss drugs in mice. In it, the team reported that they investigated the small-molecule GLP-1s including Eli Lillys recently approved drug orforglipron, also known by the brand name Foundayo, as well as danuglipron, an oral GLP-1 that was being developed by Pfizer until the company decided to discontinue its development in 2025
3.3.3 MGBA mechanisms in anxiety SCFA producing taxa is depleted in anxiety disorders (Burton et al., 2023), mirroring patterns observed in other psychiatric conditions (Bruun et al., 2024)
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