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We retested these compounds in IMR90 ER:RAS cells, and in a melanoma cell line, SK-MEL-103, in which we induced senescence by treatment with the chemotherapeutic agent etoposide or the Aurora kinase inhibitor tozasertib (Supplementary Fig

This trend is sometimes dubbed leanmaxxing

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Male C57BL/6 mice (10 weeks old) were anesthetized with isoflurane, and mesenteric arteries were then isolated and placed in ice-cold KrebsHenseleit solution, containing 112 mM NaCl, 5 mM KCl, 25 mM NaHCO 3 , 1 mM NaH 2 PO 4 , 0.5 mM MgCl 2 , 2.5 mM CaCl 2 , and 11.5 mM glucose

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Methods such as microencapsulation and nano-ncapsulation protect probiotics from stomach acid and bile, ensuring controlled release in the intestines [86]