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Moreover, rotenone induces astrogliosis and alterations in the expression of g-tubulin, signal transducer and activator of transcription 3 (STAT3), and connexin 43 in astrocytes [70, 72, 74]
Product Specifications Compound: AOD-9604 Class: Synthetic peptide fragment / growth hormone C-terminal analog Origin: C-terminal fragment of human growth hormone (residues 177-191) with N-terminal tyrosine addition Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe Molecular Weight: ~1815 Da Form: Lyophilized powder Vial Size: 5mg in 3mL glass vial Purity: 99%+ verified by HPLC and mass spectrometry (See COAs) Research Context AOD-9604 is utilized in research applications involving peptide chemistry , growth hormone fragment research , and cellular research applications
Glutamate-cysteine ligase protects cells from ferroptosis by decreasing glutamate levels, converting them to -glutamyl peptides, and boosting GSH production (36) ( Figure 1 )
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