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The elevated DNA damage and altered DNA methylation are risks for cancer and play essential roles in neurological, and developmental abnormalities and cognitive defects (66)

Cells 11 (1), 14

The results of this trial were quite interesting and have been published internationally, plasma thiamine levels of both thiamine and placebo groups were significantly depleted as compared to normal controls

Therapeutic interventions in the vicious cycle of oxidative stress and neuroinflammation could offer a promising method for treating neurodegenerative diseases

Specific cytokines such as interferon-gamma (IFN-), IL-2, and granulocytemacrophage colony-stimulating factor promote the development of AITD (65)

As such [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40], they would fully eliminate concerns extended to Parkinsons disease and Alzheimers disease by Jzwiak and collaborators review [1]