Most safety data comes from trials spanning 25 years, which is relatively short in chronic disease management
44 Under specific conditions, the demand for ALC may exceed the capacity to synthesize this essential micronutrient
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GLP-1s may additionally impact other physiological changes observed in the perimenopausal period, including vasomotor symptoms like hot flashes and night sweats, declines in bone health, and unhealthy changes in body composition (gains in fat mass and declines in muscle mass), but whether these impacts are beneficial or harmful for women's health remains unknown
This is important to reduce the risk of euglycaemic diabetic ketoacidosis
Pregnant or breastfeeding individuals should seek medical guidance