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As NAD+ supplementation research has expanded dramatically, the discovery that NNMT depletes NAD+ precursors specifically in metabolically dysfunctional fat tissue provides a targeted intervention point

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Moreover, it helps you push far past your normal point of failure during intense exercise as the added energy prevents you from prematurely burning out

A 2018 study found 5-amino-1MQ increased NAD+ by up to 40% in cultured adipocytes, but this cellular change precedes noticeable effects by weeks

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