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Symptoms may include hives, itching, swelling, dizziness, or difficulty breathing

This mechanism increases nitric oxide production, which is essential for endothelial cell proliferation, vessel dilation, and new capillary formation

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The standard regimen involves 1 mg (1000 g) administered intramuscularly on alternate days until there is no further improvement in symptoms, followed by maintenance injections of 1 mg every two months