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Common causes include: Anxiety, depression, PTSD, and neurodegenerative conditions like Alzheimers and Parkinsons disease are tightly intertwined with insomnia: Women experiencing menopause and individuals with thyroid dysfunction often report severe insomnia: Given the intricate interplay of neural, hormonal, immune, and psychological contributors, conventional therapies offer limited scope in addressing insomnia at its roots

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Interestingly, loss of motor neurons in ALS is mainly through induction of the apoptotic pathway (Vogt et al., 2018)

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Ipamorelin, on the other hand, has a distinct advantage in its selectivity