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This dual-focus strategy not only emphasizes the significance of managing uremic toxins but also highlights the necessity of personalized interventions to better protect CKD patients from cardiovascular complications

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For instance, the active exclusion of Ca 2+ from the cytosol is impaired, 43 and the resulting increase in cytosolic Ca 2+ induces its uptake by mitochondria, leading to mitochondrial dysfunction and the opening of the mitochondrial permeability transition pore (MPTP)as a cause of cell death

It introduces uncertainty about what you are actually injecting

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