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All participants reported chronic widespread pain, muscle stiffness, fatigue, poor sleep, and mood disturbances consistent with FM diagnostic criteria [35]

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Ann Clin Biochem Int J Lab Med 52(4):448455 Castro R, Rivera I, Ravasco P, Jakobs C, Blom HJ, Camilo ME, de Almeida IT (2003) 5,10-Methylenetetrahydrofolate reductase 677CT and 1298AC mutations are genetic determinants of elevated homocysteine

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The protective effects of tocopherols and vitamin E on cognitive function remained significant even after adjusting for APOE4 status [1,10]

This can happen for a variety of reasons, including genetics, gut imbalances, or chronic health issues