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Predictive computational tools are emerging to de-risk these platforms, but thorough in vivo assessment is indispensable ( 4 Challenges, future directions, and the promise of precision medicine 4.1 Key challenges in targeting oxidative stress for MIRI treatment Despite compelling preclinical evidence highlighting the central role of oxidative stress in MIRI pathophysiology, translating these findings into effective clinical therapies has proven remarkably challenging, largely contributing to the unmet promise observed thus far

Personally I think I may have had a drop in my potassium levels as I cant think of any other reason for my symptoms

doi: 10.1111/jcpt.13230

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As more patients are treated with these therapies, it is important to understand how they alter clinical presentations and risk for adverse effects