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Using a long-term HFD-fed mouse model of NAFLD, we demonstrated in this study that NAFLD development occurs concomitantly with dysregulated hepatic glutathione homeostasis characterized by decreased GSH and increased GSSG, and increased TNF protein levels in both the circulation and the liver

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In a pancreatic cancer mouse model, the small molecule N6-furfuryl adenine 11 (N6F11) selectively triggers GPX4 degradation in tumor cells, inducing ferroptosis

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He doesnt get it hardly at all now and when it does, it only comes in a small patch on his legs, whereas before he was screaming in pain from the rash

Nature 593 , 586590 (2021)