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A 2021 peer-reviewed review of NNMT in obesity and type 2 diabetes states explicitly that 'clinical trials targeting NNMT have not been reported' meaning every quantitative efficacy figure available for this compound comes from mice, and there is currently zero published human efficacy data

If you find yourself forgetting things more than usual or struggling to stay sharp, a B12 injection could make a noticeable difference within days

Clin Toxicol 1993;31:277-94 12

Can Boost Mood & Alleviate Symptoms Linked to Depression

Uses/Benefits of Vitamin B-12 Shots Here are some of the top benefits/uses of vitamin B-12 shots (Fun fact: they are all backed by science): Prevention of Anemia and Formation of Red Blood Cells Vitamin B12 helps your body produce red blood cells and fight anemia

If your doctor suspects or knows that you also need B, they will likely prescribe it separately