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252 Exposure to plasma from obese individuals promoted the apoptosis, DNA damage, and mitochondrial dysfunction of PBMCs, resulting in increased production of IL-1 and IL-8

bile acids and intestinal metabolites serve as mediators

It also leaves the door open to allergic reactions or overdoses that could prove fatal to an individual

In hemodialysis patients, elevated levels of AOPPs have exhibited a positive correlation with plasma myeloperoxidase activity (74) and oxidized fibrinogen was identified as a principal molecule contributing to the positive chemical reaction to AOPPs (75, 76)