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The lack of follow-up studies, combined with concerns regarding opioid-associated neurodevelopmental effects observed in animal models and observational human studies, necessitates cautious application and ongoing neurodevelopmental surveillance (107, 139)

doi: 10.1016/j.bmc.2013.05.065 51 GaoC.JiangJ.TanY.ChenS

This dose is lower than the US Upper Limit

Niacin ameliorates neuro-inflammation in parkinsons disease via GPR109A

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