ALC performs a variety of crucial functions, such as promoting acetyl CoA absorption into mitochondria during oxidation of fatty acid, increasing acetylcholine synthesis, accelerating protein and transmembrane phospholipid formation, and preventing undue cellular injury in the neuron (Di Cesare Mannelli et al., 2011)
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The dimerization process involves initial binding of magnesium to the aspartate in the starter sequence which inturn interacts with the pyrophosphate molecule of the thiamine diphosphate through hydrogen bonding [101], followed by one transketolase monomer engaging the pyrophosphate moiety and the other with the thiazolium and pyrimidine rings of ThDP [88, 97]
Both are unapproved research chemicals, and both appear on the WADA prohibited list under S2, so they carry no approved-therapeutic status of any kind
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