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The conditions are classified into 3 categories of severity based on the percentage of body surface involved: SJS: lesion area is less than 10% SJS/TEN overlap: lesion area is 10% to 30% TEN: lesion area is greater than 30%

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De esta forma, los fluoruros afectan a la fase de secrecin en los ameloblastos, ocasionando una reduccin en la produccin de protenas, secrecin y concentracin de las mismas ocasionada por la respuesta al EO, lo que origina un dao en el proceso de mineralizacin22,23,29,30

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