Some users do lose weight, but that usually reflects diet, activity, and motivation changes happening at the same time, not the patch itself crossing the skin barrier and acting like a drug
Last reviewed: June 27, 2026 Last updated: June 27, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
These medications include semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)though tirzepatide is technically a dual GIP/GLP-1 receptor agonist with a slightly different mechanism
Over the years, the FDA has issued hundreds of warnings about tainted weight loss products that could lead to serious health problems
Quick Answer: GLP-1 medications typically cause modest blood pressure reductions of 2-6 mmHg, but some patients may experience symptomatic low blood pressure, particularly when combined with antihypertensive medications, significant weight loss, or dehydration from gastrointestinal side effects
36 GLP-1R GLP-1R, a member of the GPCR family, exhibits specific affinity for GLP-1