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Research focus Summary of contexts in which this compound appears in the preclinical literature

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The glucose-lowering effect of GLP-1 RAs primarily operates through stimulating insulin secretion, inhibiting glucagon release, and reducing hepatic glucose production

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Finally, although the correlations between the metabolome and microbiome were established using robust statistical analyses, there was limited statistical power and there are also limitations to the statistical approaches used herein (e.g., log transformation to resolve non-normal distribution and/or heteroscedasticity 103 )