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The doc explains that when you boost your prebiotic intake, you prod your body to produce more of its own GLP-1 hormones

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Meanwhile, mTORC1/S6K1 can also phosphorylate IRS-1 serine, thus block its activation 80 (Fig

doi:10.1124/pr.115.011395 Wootten D, Simms J, Miller LJ, Christopoulos A, Sexton PM