Due to the multisystemic symptoms, MCAS can be very difficult to correctly diagnose and manage
Rethinking peripheral T cell tolerance: checkpoints across a T cells journey
Reid MA, Salibi N, White DM, Gawne TJ, Denney TS, Lahti AC

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The Olympic Committee introduced a definition of doping: the use of foreign substances in abnormal quantities to enhance performance
Its plasma levels decline significantly with age (from ~200ng/mL at 20 to ~80ng/mL at 60), making it a key compound for aging biology and regenerative research