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Defective Immunogenic Cell Death of Hmgb1-Deficient Tumors: Compensatory Therapy With TLR4 Agonists

Low WY, Feil SC, Ng HL, Gorman MA, Morton CJ, Pyke J

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Recently, metabolomics has become a valuable tool in disease diagnosis and drug target evaluation [271]

We wondered whether inhibition of TS in cells surviving 5FU treatment promoted the observed reprogramming of mitochondria towards increased biogenesis and activity