These observations suggest that the loss of endothelial cell antithrombotic function combined with the induction of a procoagulant state may contribute to the vascular disorders linked to moderate hyperhomocysteinemia
During this time, cells begin to change and respond
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High homocysteine levels can also be caused by low vitamin B12 levels because vitamin B12 is the cofactor needed by the enzyme responsible for converting homocysteine to methionine
24 , 25 The follicles were smaller and markers of activated follicular recruitment and increased apoptosis were evident, suggesting follicular burnout
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