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4.2 Dysbiotic microbiome stimulates cyclooxygenase-2 expression, affects gastric emptying, and induces GERD Cyclooxygenase-2 (COX-2) is the rate-limiting enzyme that catalyzes the initiating step in the metabolism of arachidonic acid to prostaglandin H2 and is a precursor to prostaglandins such as prostaglandins, thromboxanes, and prostacyclins, which act as autocrine and paracrine lipid mediators in the maintenance of local homeostasis by mediating vascular function, wound healing, and inflammation (52)
examined 41 tissue samples (including 9 papillary thyroid cancer tissues) (97) and found that their Se levels and GPx activity were lower than those of non-cancerous tissues, while malondialdehyde (MDA) concentrations were increased
Bifidobacterium infantis : , ,
Any GLP-1 connection is indirect at best
