glp 1 benefits beyond weight loss GLP-1 and health: in the Ozempic era GLP-1 medications are changing outcomes

I hadn't realized how impossible this research is until I read some of Alessio Fasano's research (Mass General

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Kaiser Permanente Northwest, prior authorization criteria for GLP-1 anti-obesity agents California Medi-Cal dropped GLP-1 obesity coverage effective January 1, 2026, eliminating the weight-loss Wegovy pathway for Kaiser Medi-Cal members in California

Methods Sixty-eight subjects (1875 years

The mechanism is central, not peripheral

Hexokinase-2 associates persistently with both VDAC1 and VDAC2 77 , with a stronger preference for VDAC1 in many contexts, while hexokinase-1 primarily associates with VDAC1 78