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Nonetheless, even though an IN chelator enters the brain, its distribution is unlikely to be region-selective, which is a major limitation

What to Expect After B12 Injections The effects of B12 injections can vary from person to person

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Indeed, melatonin is highly permeable to cell membranes and easily crosses the bloodbrain barrier 51 , ensuring a good therapeutic profile for brain diseases, and is also able to accumulate into mitochondria, probably via GLUT/SLC2A and PEPT1/2 carriers 52,53

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