Alterations on the delivery of nutrients to the small intestine resulting from the fundoplication, which decreases the accommodating capacity of the stomach, may explain the rapid rise in glucose and enhanced GLP-1 release
A quick, firm entry is usually less painful than a slow, hesitant one
Although an increase in heart-rate per se is not a major problem for most people, it is salient in the case of GLP1R, GIPR or GR agonists since the target patient population of these agonist are obese patients, who likely already suffer from cardiovascular complications
In clinical practice, most people maintain their weight throughout the transition, especially when lifestyle habits are maintained
For more frequent or troublesome reflux, proton pump inhibitors (PPIs) such as omeprazole or lansoprazole, or H2-receptor antagonists like famotidine may be recommended by a GP
Additionally, it has shown potential benefits for hair appearance, reducing hair loss, and even neuroprotective effects, such as mitigating amyloid plaque formation
