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Injection site reactions including erythema, pruritus, or mild indurationoccur in some patients, with frequency varying by product (from low single-digit percentages to over 10%)

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Moreover, the available reports do not allow confident separation of direct drug-related reproductive effects from mediation through weight loss and improvement in insulin resistance

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For men who desire pregnancy within six months and have been on TRT, some practitioners recommend discontinuing testosterone entirely and increasing HCG to 3000 IU every other day

2025 systematic review in HSS Journal screened the full BPC-157 musculoskeletal literature through June 2024 and found a large preclinical base tendon, ligament, muscle, bone, and nerve injury models but only one published human exposure dataset, the small open-label knee-pain case series