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A Case Method Approach

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RIBBON-2: A randomized, double-blind, placebo-controlled, phase III trial evaluating the efficacy and safety of bevacizumab in combination with chemotherapy for second-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer

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A: Surgical diagnosis should be reserved for cases where clinical diagnosis is uncertain, empirical treatment has failed, or surgical treatment is indicated for other reasons