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Medical and Editorial Review This final article has been reviewed for medical context, evidence presentation, patient safety language and editorial clarity by the multidisciplinary panel below

The goal is to find your personal optimal dose, the highest amount you can tolerate without significant issues while achieving your desired results

Live-cell microscopy RAW 264.7 macrophages were seeded in Nunc 8-well Lab-Tek chambered coverglass (ThermoFisher) at 23 10 5 cells per well in 500 l complete minimum essential medium (MEM, Gibco) supplemented with 10% (v/v) heat-inactivated FBS and 2 mM L-glutamine at 37 C with 5% CO 2 for 16 h

Med Res Rev 43(3):614682

60 SchnekenburgerM.DiederichM

For personalised advice and a professional assessment of your B12 needs, always consult a qualified healthcare provider