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Most patients report that later-stage nausea (if it occurs) is milder and shorter-lived than the initial onset

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STEP-HFpEF Trial Committees and Investigators, Kosiborod MN, Abildstrm SZ, Borlaug BA, Butler J, Rasmussen S, Davies M et al (2023) Semaglutide in patients with heart failure with preserved ejection fraction and obesity

Offered in a lyophilized powder form, they are typically used in research to their effects on fat storage and energy utilization in cells