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In summary, our urine results indicate that weight loss through GLP-based therapies is not associated with prolithogenic changes in 24-hour urine chemistry in patients with nephrolithiasis, unlike what happens with alternative weight loss modalities (such as malabsorptive bariatric surgery and pharmacological therapy with orlistat or topiramate)

They are individually housed in metal cages in an air-conditioned room (22 2C, 55 5% humidity), under a 12 h light/12 h dark cycle with free access to food and water

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Seek same-day medical assessment if you develop sudden, severe joint pain, particularly if accompanied by redness, swelling, or fever, to exclude septic arthritis and receive appropriate treatment