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Retatrutide, a GIP, GLP-1, and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial
injections of 100 nmol kg 1 GLP-1 ( n = 6 mice), 100 nmol kg 1 GLP-1MK-801 (Pen-linked) ( n = 6 mice) or vehicle (isotonic saline, n = 6 mice) for 7 days
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Peptides are short chains of amino acids, the building blocks of proteins
[Abstract] Compared with guinea pigs receiving periocular injections of vehicle (5 mM, 10 L on days 1, 4, 7, 10, and 13 over two weeks), those treated with glutathione oxidized (Glu, 20 mg/mL, 10 L on the same schedule) exhibited a 1.76-fold increase in relative myopia, along with a 1.78-fold increase in axial length (AL)