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doi: 10.1016/j.amjmed.2023.07.016

17-19 NEXT: Common Indications of DOACs, Common Indications of DOACs Since their development, DOACs have been compared with conventional anticoagulation therapy in many major studies

Rare hypersensitivity reactions , including cobalt allergy (as cobalamin contains cobalt), have been documented

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Lastly, epithalon plays a significant role in the endocrine system by increasing levels of endogenous hormones that naturally diminish with age, such as melatonin (which helps regulate the sleep cycle), and gonadotropic hormones (FSG, LG, prolactin), which play a role in reproductive functions [8]