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Specifically, starting from a closed conformation in apo state, the ECD of GLP-1R bound by either compound 2 or truncated peptide agonist (peptide 5) 10 rotated clockwise and approached to ECL1 and ECL2

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However, the study did not find significant associations with several common cardiac and metabolic disorders, including type 2 diabetes, hypertension, chronic kidney disease, ischemic heart disease, and congestive heart failure

CJC-1295 (No DAC) is a short-acting peptide studied for its role in stimulating growth hormone release in a pulsatile manner

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