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Distribution and excretion of carnitine in the rat

doi: 10.1172/jci72434 56 HayesMRSkibickaKPGrillHJ

For instance, in human hepatocellular carcinoma cell lines (HCCLM3 and HepG2), overexpression of GRK2 inhibits IGF1R signaling activation, the activation of PI3K/AKT and MEK/ERK pathways, and the expression of early growth response protein 1 (EGR1), which results in the suppression of proliferation and migration of cells