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LY3437943 has shown a powerful effect in reducing liver fat and liver injury markers in obese mice, which may be attributed to a combination of GCGR's direct impact on the liver or the indirect effects resulting from weight loss

The branded drug may attempt to compete on net price by offering very large rebates, but this strategy erodes margins and rarely succeeds in maintaining meaningful formulary position against established generic competition

Others take months

So if a person loses 50 pounds less than 12 and a half of those pounds should be lean mass, that would be really, really ideal

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