These studies also noted that no adverse cardiovascular effects were observed [54]
Stay Hydrated : Vomiting or diarrhea can lead to dehydration, so stay hydrated, especially in the first few weeks
On February 6, however, FDAs approach appeared to shift with an announcement that it would be taking steps both to restrict GLP-1 active pharmaceutical ingredients (APIs) that continue to be used in non-FDA-approved compounded products to combat misleading direct-to-consumer advertising and marketing. Unequivocally, FDA warned: Entities engaged in the manufacture, distribution, or marketing of unapproved compounded GLP-1 products should be aware that failure to adequately address any violations may result in legal action without further notice, including, without limitation, seizure and injunction. FDA specifically named Hims & Hers a popular and outspoken telehealth provider that advertises compounded GLP-1 products in the announcement
Further Information and Verification
Furthermore, early safety trials that included kidney outcomes as secondary endpoints hinted at potential renal benefits associated with these medication classes
At 72 weeks, tirzepatide resulted in 20.2% average weight loss compared to 13.7% with semaglutide
