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Considering the connection between Nrf2 and glutathione, researchers have investigated the role of Nrf2 in preventing cataract formation in animal and human lenses

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PubMed:17018654 Jette, L., et al

Titration should be gradual to minimize side effects, but it typically takes 1620 weeks to reach therapeutic levels

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Chan SH, Tai MH, Li CY, Chan JY: Reduction in molecular synthesis or enzyme activity of superoxide dismutases and catalase contributes to oxidative stress and neurogenic hypertension in spontaneously hypertensive rats