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Sexton (Monash University, Melbourne, Australia)

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doi:10.3390/jcm10091891

Some contain natural ingredients, such as berberine, pomegranate extract, cinnamon, and L-glutamine

However, past pancreatitis is not a contraindication for these agents, and contrary to the previous warning, recent studies have not shown an increased pancreatic risk associated with GLP-1 RAs, leading to ongoing revisions in treatment guidelines

Before prescribing any GLP-1 medication, clinicians should take a thorough personal and family history specifically enquiring about thyroid cancer, particularly MTC, and any known hereditary endocrine syndromes