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CAT expression/activity frequently declines during malignant transformation, including HCC, and lower CAT levels are linked to worse outcomes

It plays a crucial role in various physiological processes and is primarily taken as a supplement because it is a powerful antioxidant that helps protect cells from oxidative stress and damage caused by free radicals

In this study, the rate of any grade of irAEs was high (93.5%) and 49% of patients experienced severe ( grade 3) irAEs

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In addition, in the Adriamycin-induced FSGS model rats, the relative abundances of Lachnospiraceae _ NK4A136_group and Prevotellaceae _ UCG-001 were reduced, while [Ruminococcus]_torques_group abundance was increased [149]