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Bioavailability from oral supplementation is notoriously low estimates range widely, but studies consistently show significant degradation occurs before meaningful absorption
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Vaporciyan AA, Correa AM, Rice DC, Roth JA, Smythe WR, Swisher SG , Walsh GL, Jr PJ
Evidence that acetaminophen and N -hydroxyacetaminophen form a common arylating intermediate, N -acetyl- p -benzoquinoneimine
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