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In human studies, pramlintide, acting as an amylin analog, slows gastric emptying, reduces the postprandial rise in plasma glucagon, and modulates satiety leading to decreased caloric intake

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Gastrointestinal Adverse Effects of GLP-1 and Dual GLP-1/GIP Receptor Agonists: A Comprehensive Update in Diabetic and Obese Populations

10.1097/wnr.0000000000001988 110 MaguireE

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Semaglutide should be used under guidance from your doctor, given individual variations and eligibility criteria, and dieting and exercise remain ideal solutions when attempting sustained weight management goals in nondiabetic individuals