Mild nausea, reduced appetite, and earlier fullness are common
Research shows an average recovery of 40-50% of lost weight in the first 12 months post-discontinuation, though individual variation is wide
For example, Kaiser Permanente Northwest Region covers Wegovy as a prescription drug benefit if patients meet the following criteria: Have been diagnosed with chronic weight management Are 18 years or older Have documented their current weight and body mass index (BMI) Are actively following a diet and exercise program Have a BMI of 30 or higher or have a BMI of 27 or higher, plus hypertension, diabetes, or hyperlipidemia Failed a three-month trial or has an allergy, intolerance, or contraindication to phentermine, diethylpropion, Qsymia, and Contrave Failed a three-month trial of Ozempic Medicare doesnt cover medications strictly for weight loss, so Kaiser Medicare Part D plans typically wont cover Wegovy for weight loss alone

Acronyms A1C - Hemoglobin A1C ADA - American Diabetes Association CVD - Cardiovascular disease DM - Diabetes mellitus FBS - Fasting blood sugar GFR - Glomerular filtration rate GI - Gastrointestinal GLP-1 - Glucagon-like peptide-1 OSA - Obstructive sleep apnea RCT - Randomized controlled trial T2DM - Type 2 diabetes mellitus Thyroid C-cell tumor = Thyroid medullary tumor DRUGS IN CLASS Dual GLP-1 and GIP agonists Tirzepatide (Mounjaro) - marketed for diabetes Tirzepatide (Zepbound) - marketed for weight loss MECHANISM OF ACTION GLP-1 and GIP GLP-1 stands for "glucagon-like peptide-1," and GIP stands for "glucose-dependent insulinotropic polypeptide." GIP is also sometimes referred to as "gastric inhibitory polypeptide." GLP-1 and GIP are hormones secreted by specialized cells in the small intestine in response to food consumption

PlexusDx offers the Precision Peptide Genetic Test, which identifies your peptide-pathway genetic predispositions across 14 metabolic pathways and 150+ insightsincluding how your FTO, GLP1R, MC4R, and GIPR variants influence hunger, satiety, and food preferences
GLP-1 medications are drugs that mimic the hormone glucagon-like peptide-1 , which helps regulate hunger, insulin production, and blood sugar levels