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The history of medicine is full of compounds that healed rodents and harmed people

The 10X group dogs had increased hematocrit, hemoglobin, RBC counts, urine specific gravity, and water intake consistent with transient, sub-clinical dehydration that occurred shortly after PPA treatment was started

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Development of cyclosporine A as immunosuppressive drug has been traced back to the stimulus derived from the first highly-active cyclopeptides from [188]