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Mech Ageing Dev (2002) 123:112131
Its almost a question of where are they not ? In fact, these receptors are now known to be abundant throughout the body
Reported complications described in some GLP-1 drug claims have included: Severe or persistent gastrointestinal symptoms , such as ongoing nausea, vomiting, or abdominal pain Delayed stomach emptying (gastroparesis) , which has been described by some individuals as involving bloating, nausea, vomiting, or difficulty tolerating food Intestinal complications , including reduced bowel activity (ileus), which may involve abdominal discomfort, cramping, or vomiting Gallbladder-related conditions , such as gallstones or gallbladder inflammation Blood-clot-related conditions , including deep vein thrombosis or pulmonary embolism, described in some reports and legal filings Vision-related problems , including reports involving non-arteritic anterior ischemic optic neuropathy (NAION) discussed in connection with semaglutide in certain contexts Not everyone who takes a GLP-1 medication experiences these issues, and the relationship between GLP-1 drugs and reported complications continues to be evaluated in legal proceedings
In clinical studies, participants reached maximum weight loss between weeks 60-72
Importantly, clinicians must exclude mechanical obstruction and other organic pathology before attributing symptoms to gastroparesis
PubMed Misaka S, Ono Y, Taudte RV, et al
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