33,34,35,36,37 One study suggests that length of time from diagnosis of cognitive impairment is important for response rate, in that patients who had experienced symptoms for less than 12 months improved on B12, whilst those with symptoms for more than 12 months continued to decline
However, it failed to provide any notable therapeutic benefit in most patients and in some even produced adverse effects
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If you are supplementing to support liver health, frequent alcohol use may limit the "gains" you see from your routine
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Frezza, C