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Flomenbaum, Goldfrank, Hoffman, Howland, Lewin & Nelson (Editors)

10.3389/fimmu.2024.1520072 90 WeiC.-Y.ZhuM.-X.LuN.-H.PengR.YangX.ZhangP.-F.et al (2019)

Another study observed disruption of the motility cycle in mice treated with high-dose fluoxetine

These changes were accompanied by increases in sperm morphological defects, testicular histology revealing the presence of germ cells, and severe degeneration of supporting and mesenchymal cells

Additionally, they were provided with unrestricted access to food and water to ensure their wellbeing

Overall, these data suggest a relatively understudied connection between dopaminergic modulation of immune function and bipolar disorder and indicate that the combination of anti-inflammatory and dopaminergic drugs could provide more beneficial alleviation of bipolar symptomatology than individual treatment