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Conclusion The 3Ts Protocol integrates pharmacologic vascular optimization, biologic activation via intralesional tunneling, and traction-induced mechanomodulation to concurrently target the vascular, fibrotic, and structural components of PD

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The shear stress, representing shear force per unit area, is particularly elevated near the vessel wall with values ranging from 1 to 4 dyn/cm 2 in veins, and 430 dyn/cm 2 in arteries [219]

Leung HWC, Chan ALF

Total runs $1,600-$3,200 depending on whether the patient adds laser or microneedling

doi: 10.1016/j.redox.2023.102827